MIMM 314 Chapter Notes - Chapter 2: Respiratory Burst, Kupffer Cell, Mannose

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magentacricket108

14 May 2012

School

McGill University

Department

Microbiology and Immun (Sci)

Course

MIMM 314

Professor

Dr.Palfree

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Document Summary

Phagocytes may take up the pathogen before it enters cells, while nk cells can directly recognize and kill cells infected with some intracellular pathogens. Nk cells are instrumental in keepeing some viral infections in check until an air has been generated, after which ctls are ableto take over the role of killing virus-infected cells. Some diseases include smallpox, hepatitis, plague, meningitis, pheumonia, diphteria, Some diseases include: tuberculosis, rheumatic fever, hemolytic anemia, kidney disease. Antimicrobial proteins and peptides, phagocytes, and complement destroy invating microorganisms; Dcs migrate to lymph nodes to initiate air. Enzymes pepsin) bacterial peptides enzymes in tears (lysozyme) Other antibacterial and antifungal peptides mentioned in the book: cryptidins or alpha-defensins (peneth cells), beta-defensins, commensal bacteria (nonpathogenic bacteria) Macrophages are found in different tissues, and thus they sometimes get different names, such as: More often, macrophages are referred to as mononuclear phagocytes.

Related Questions

There are basically three different types of pathogen invasion âstrategiesâ â extracellular, intracellular in non-phagocytes like epithelial cells, and intracellular in circulating phagocytes like Macrophages. That is, some bacteria try to remain outside of the host cells, while other bacteria and viruses get inside different types of host cells and survive there.

A. For EXTRACELLULAR pathogens, describe advantages and disadvantages of this strategy. How does our immune system detect and eliminate such pathogens? Explain two virulence factors that this sort of pathogen can use to survive in its chosen environment.

B. For pathogens that are INTRACELLULAR IN MACROPHAGES, explain how they gain access to macrophages. Describe advantages and disadvantages of this strategy. How does our immune system detect and eliminate such pathogens? Explain two virulence factors that this sort of pathogen can use to survive in its chosen environment.

C. For pathogens that are INTRACELLULAR IN EPITHELIAL CELLS, explain how they enter the epithelial cells. Describe advantages and disadvantages of this strategy. How does our immune system detect and eliminate such pathogens? Explain two virulence factors that this sort of pathogen can use to survive in its chosen environment.

purplelion816

IMMUNOLOGY

1.If an individual is homozygous at his MHC I genes, but heterozygous at his MHC II genes, how will that affect his immune protection against extracellular pathogens versus intracellular pathogens?

which of the following is a facultative, rather than obligate, intracellular pathogen?

What do you mean by intracellular pathogen. Give some examples of facultative and obligate intracellular pathogen.

ivorygrasshopper870

MIMM 314 Chapter Notes - Chapter 2: Respiratory Burst, Kupffer Cell, Mannose

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