NSCI 201 Chapter Notes -Anaerobic Glycolysis, Nmda Receptor, Blood Sugar

• School: McGill University
• Department: Neuroscience
• Course: NSCI 201
• Professor: Evan Balaban

Document Summary

Neurotransmitters and action potentionals a single epsp or ipsp is transitory glutamate: most important excitatory nt - released by 90% of all neurons opens na+ channels (na+ flows into the cell) Na+ flux into the neuron decreases the electric potential glutamate nmda receptor: admits ca2+ into the cell after a post-synaptic membrane potential is reached. Gaba: influx of cl into the neuron or efflux of k+ out. Cerebral metabolism: neuronal energy consumption blood glucose conc. Cl- ions move down a smaller electrochemical gradient then the na+ ions inhibitory synapses are outnumbered by excitatory synapses sodium-potassium pump is the main energy consumer in the brain. The vascular system of the brain blood volume is relatively constant over time even if the local blood flow changes. 15-20% of blood flows to the brain brain consumes ~20% of blood oxygen - metabolism is directly correlated to capillary density. Areterial and venous anatomy of the human brain.