PHGY 314 Chapter Notes - Chapter 66: Adenylyl Cyclase, Temporal Lobe, Implicit Memory
23 Sep 2017
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Implicit memory: unconscious and automatic, habits & motor skills: requires the neocortex for priming, striatum for skills/habits, amygdala for learned fear, cerebellum for learned motor skills, explicit memory: conscious, for people, places and objects. Info can transfer from explicit to implicit memory. Initially inactive form of prion protein, gets activated when reach certain [c] of serotonin -- activates mrna translation: self-perpetuating, leads to persistent memory storage, much of molecular mechanism conserved in mammals and other species (i. e. flies) Info goes from thalamus to cortex to amygdala: synaptic transmission enhanced through insertion of ampa-glutamate receptors in postsynaptic membrane & increase is transmitter release, ltp provides cellular mechanism for storage of learned fear memory. Striatum: necessary of habit learning & memory, through repetitive stimulus-response conditioning, learn simple behaviors that then combine into complex behaviors, basal ganglia has 4 nuclei, striatum (input nucleus, globus pallidus, substantia nigra, subthalamic nucleus.
