PSYC 211 Chapter Notes - Chapter 18: Striatum, Opioid Receptor, Indirect Agonist
Document Summary
Addiction latin word addicere to sentence" in term of involuntary servitude, being obliged to fulfill the demands of his or her drug dependency. Long ago, people discovered that the natural plants contains the medicinal characteristics, can reduce pain, prevent infections and also induces sleeping. They also discovered the recreational drug" = this gives the pleasurable effects when eaten, drunk or smoked. Positive reinforcement this refers to the effect the certain stimuli have on the behavior that preceded them. Nmda receptor (indirect antagonist), gaba receptor (indirect agonist) Nicotinic ach receptor (agonist) miu and sigma opiate receptor (agonist) antagonist) Blocks reuptake of dopamine (and serotonin and norepinephrine) Causes release of dopamine (by running dopamine transporters in reverse) reinforcing effects. Role in drug abuse the most potent reinforcement occurs when drugs produce sudden changes in the activity of the reinforcement mechanism; slow changes are much less reinforcing.