PSYC 311 Chapter Notes - Chapter Reading 22 - Post Midterm 3 - H+A+ Lesions - Squire: Temporal Lobe, Parahippocampal Gyrus, Hippocampal Formation
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Reading 22: the medial temporal lobe memory system larry r. squire: Memory system: hippocampus and adjacent anatomically related cortex, including entorhinal, peri-rhinal, and parahippocampal cortices. These structures are essential in establishing long term memory for facts and events. The role of this system is only temporary as time passes after learning, memory stored in the neocortex gradually become independent of medial temporal lobe structures. The medial temporal lobe is a large region that includes the hippocampal formation, the amygdaloid complex, and adjacent cortical areas. It has been difficult to determine from human cases precisely which structures and connections within the medial temporal lobe are important for memory. Initially, attention was drawn to the hippocampal region because patients who underwent temporal lobe surgery developed memory impairment only when the removal extended far enough posteriorly to include the hippocampus and parahippocampal gyrus. However, memory functions were not assessed formally, and damage in most cases was not confined to the hippocampus.