BIOCHEM 3G03 Chapter Notes - Chapter 3: Nucleoside Triphosphate, Nucleotide, Horizontal Gene Transfer

• School: McMaster University
• Department: Biochemistry
• Course: BIOCHEM 3G03
• Professor: Daniel Yang

Document Summary

Mendel: first to describe predictable patterns of inheritance: later on me(cid:374)del"s i(cid:374)he(cid:396)ited fa(cid:272)to(cid:396)s (cid:894)ge(cid:374)es(cid:895) (cid:449)e(cid:396)e (cid:396)e(cid:272)og(cid:374)ized as (cid:271)elo(cid:374)gi(cid:374)g to chromosomes (cid:894)(cid:862)(cid:272)olou(cid:396)ed (cid:271)odies(cid:863)(cid:895) Avery, macleod, mccarty: showed substance from dead pathogenic strain of bacterium that transformed cells from normal pathogenic was dna. Each nucleotide has a nitrogen-containing base: adenine (a), guanine (g) = purines, cytosine (c), thymine (t) = pyrimidines, rna: uracil instead of thymine. 5 carbon sugar: linking n9 in a purine or n1 in a pyrimidine, dna: (cid:1006)"-deoxyribose; rna: ribose. Nucleotide: nucleoside + phosphate: can be a nucleoside monophosphate, diphosphate or triphosphate. Deoxynucleotides: a(cid:271)(cid:271)(cid:396)e(cid:448)iated (cid:271)y (cid:862)d(cid:863) damp, dgdp, dctp. Building blocks for dna + rna, but may perform a variety of functions in the cell: energy transduction, intracellular signaling, regulation of enzyme activity, some are key players in metabolic pathways synthesize biomols. Coa carrier of other molecules during their synthesis/degradation two nucs linked in the compounds nad and fad that undergo reversible ox. /re.