BIOLOGY 1A03 Chapter Notes - Chapter 7: Differential Centrifugation, Nuclear Export Signal, Golgi Apparatus

• School: McMaster University
• Department: Biology
• Course: BIOLOGY 1A03
• Professor: Rosa Da Silva

Document Summary

Protein synthesis occurs at the site of the ribosome: can be embedded in the er, or can be free floating in the ribosome. Receives from the cis side and exits from the trans side. Has the property of sidedness polarity (polarity has nothing to do with charge) Consists of a large subunit and a small subunit. Contains catalase, converts hydrogen peroxide to oxygen and water. The cell recycles and reuses broken down mitochondria and other components. **real world examples of*: phagocytosis, autphagy, receptor mediated endocytosis. Distinguishes cell shapes and locations of organelles. Permits the isolation of specific cell components, such as organelles. High speeds with a longer period of time: density gradient centrifugation. Nls"s on the protein binds to other proteins called importins. Exporting is the opposite of the importing process. Exportins assist molecules possessing the nuclear export signal to exit out of the nucleus. Scientists radioactively labelled components of the produced proteins (ie amino acids)