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Chapter 12

CHEM 2OB3 Chapter Notes - Chapter 12: Pi Bond, Ozonolysis, Leaving Group


Department
Chemistry
Course Code
CHEM 2OB3
Professor
Paul Harrison
Chapter
12

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12: Synthesis
One-Step Synthesis
Refer to chapter 9 and chapter 10 reagents for one-
step alkene and alkyne reactions
Functional Group Transformations
-Reagents must be considered to ensure a Anti/Mark product is achieved
-If the OH is the leaving group, it needs to be protonated before leaving
Reactions That Change the Carbon
Skeleton
-Allkylation of a terminal
alkyne will increase the size
of the carbon skeleton
-Ozonolysis of an alkene
achieves bond cleavage at
the pi bond
Approaching Synthesis Problems
Retrosynthetic Analysis
*Analyze the last step of a synthesis first
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