HTHSCI 2H03 Chapter Notes - Chapter 4: Pharmacokinetics, Cell Membrane, Therapeutic Index
18 Sep 2017
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Document Summary
Agonist: a drug that produces the same type of response as the endogenous substance. Antagonist: a drug which occupies a receptor and prevents an endogenous chemical from acting. Cell signalling: part of a complex system of communication that enables cells to perceive and correctly respond to their environment and carry out basic cellular activities. Dose-response relationship: how the therapeutic response to a drug changes as the medication dose is increased. Efficacy: the magnitude of maximum response to a drug, are means of comparing medications. Frequency distribution curve: a graphical representation of the number of individuals who respond to a drug at different doses. Median effective dose: dose in the middle of the fdc it is the dose required to produce a specific therapeutic response in 50% of a group of clients (average/standard dose) Median lethal dose: the dose of drug that will be lethal in 50% of group of animals.
