NURSING 2LA2 Chapter Notes -Delta Cell, Glut4, Adrenal Medulla

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6 Mar 2014
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Such as hla-dr2: chromosome 11- insulin gene regulating beta cell replication and function, there is also an insulin gene that regulates beta cell replication and function on chromosome 11. Mellitus: disorder of carbohydrates, fat and protein metabolism due to insulin deficiency. Increased risk of heart disease, stroke, kidney disease, blindness, amputation, erectile dysfunction, and reduced quality of life. Etiology type 1 dm: characterized into two groups. This is believed to be a result of a genetic-environment interaction: genes, mhc genes on chromosome 6encode leukocyte antigens hla-dq and hla-dr, some leukocyte antigens are known to decrease the risk of developing type 1 diabetes. Northern hemisphere, this proposes the idea that there is a gene-environment interaction which causes type 1a diabetes to manifest. Idiopathic type 1b (non-immune type 1 diabetes): no evidence of autoimmunity, the etiology is unknown. It accounts for less than 10% of those with type 1 diabetes.

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