PSYCH 2NF3 Chapter Notes - Chapter 2: Alcohol Dehydrogenase, Bioavailability, Gastrointestinal Tract
7 Jan 2019
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Document Summary
Bioavailability: how much alcohol is available to enter the brain from the blood. Blood alcohol concentration: what behavioral effects are described on the basis of, generally takes a bac of 0. 04% to produce effects. A comparison of alcohol content of various beverages shows an equivalent amount despite differences in volume. To calculate amount of alcohol in a beverage: number of ounces x percent alcohol by volume, ex: volume of wine = 5 0z and percent alcohol = 12, therefore, ethyl alcohol by serving is 0. 6 oz. Absorption always occurs from the gi tract: 10% from stomach, 90% from small intestine. Molecules move by diffusion from higher concentration in the gi to lower concentration in the blood. Presence of food in stomach slows absorption (delays movement into small intestine) Gender differences in absorption: enzymes (alcohol dehydrogenase) 60% more active in men (leaving higher concentration of alcohol absorbed more rapidly in women) Asian population: means they exhibit unpleasant response to alcohol.
