BCHM 316 Chapter Notes - Chapter 16.1*: Acetoacetyl-Coa, Acetyl-Coa, Terpenoid
Steps in the synthesis of isoprenoids (sans enzymes)
- Acetyl coA (2 C) + acetoacetyl coA (4 C)
- HMG coA (6 C)
- Mevalonate
- Mevalonate-PP
- Isopentenyl-PP
- Geranyl-PP (10C)
- Farnesyl-PP ( 15C)
- Squalene (30 C)
- Cholesterol
*** note that all of these compounds are composed of isoprene units
Isopentenyl-PP
- Isopentenyl adenine (tRNA)
Farnesyl-PP (- 15C)
- Dolichol
- Haem a
- Ubiquinone
- Fanesylated proteins
- Ras, iamin B…
Cholesterol
- Steroid hormones
- Vitamin D
- Bile Acids
- Lipoproteins
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