KNPE 225 Chapter Notes - Chapter 12: Pancreatic Islets, Diabetes Mellitus Type 1, Autoimmune Disease
4 Nov 2016
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Chapter 12 - physical activity and type 2 diabetes. Diabetes, the most common endocrine disorder, multiple organs and body functions, calling to his health complications, such as renal failure, heart disease, nerve damage, stroke, and blindness. The body cannot control the level of circulating blood glucose because of either insufficient insulin production, or inadequate response by organs to circulating levels of insulin. Insulin is the major hormone controlling the body"s glucose homeostasis, also regulates the metabolism of fats and proteins. Insulin: a polypeptide hormone secreted by the beta cells of the pancreatic islets. Explain the major differences between type 1 and type 2 diabetes. Some of the most characteristic symptoms associated with onset diabetes include frequent urination, excessive thirst, and fatigue. It is an autoimmune disorder, the cells responsible for releasing insulin, pancreatic beta cells, are mistaken by the immune system as foreigners and selectively destroyed. As a result, circulating insulin levels in the blood dramatically decreased or even disappear.
