PHAR 100 Chapter Notes - Chapter 11: Extrapyramidal Symptoms, Atypical Antipsychotic, Dopamine Receptor
11 Nov 2016
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Lesson b. 6 classification of mental disorders antipsychotic and antidepressant drugs. Differentiate between psychoses, affective disorders and neuroses. Describe the evidence that excessive dopaminergic activity underlies schizophrenia. Describe the mechanism of action of antipsychotic agents. Describe the adverse effects of phenothiazines and mechanisms responsible for these adverse effects. Differentiate between the adverse effects of phenothiazines, butyrophenones and clozapines. Describe the mechanism of action of lithium as a therapeutic agent in manic-depressive illness. List the adverse effects of lithium and one means of trying to minimize the adverse effects. Describe the types of depressants and their mechanisms of action. Describe the adverse effects of different types of antidepressants. Symptoms include: impairment of behaviour, incoherent thought processing, inability to comprehend reality or to gain insight into their abnormalities, delusions and hallucinations. Organic psychoses: causes are understood and definable (toxic induced, metabolic or neuropathological changes, characterized by confusion, disorientation, memory disturbances and behavioural disorganization.
