PSYC 271 Chapter Notes - Chapter 11: Temporal Lobe, Retrograde Amnesia, Memory Span

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Memory how these changes are stored and subsequently reactivated. Knowledge about these mechanisms has come from significant studies based on patients with brain-damage-produced amnesia (any pathological loss of memory) as well as animal studies. 1. 1 amnesiac effects of bilateral medial temporal lobectomy. H. m was a man who in 1953, at 27, has medial portions of temporal lobes removed due to extreme epilepsy. The case of h. m. , the man who changed the study of memory. Suffered from one generalized seizure each week and partial ones daily despite huge doses of anti-convulsive medication: arose from foci in medial portions of left and right temporal lobes. Decided to perform bilateral medial temporal lobectomy by removing medial portions of both temporal lobes: including: amygdala, hippocampus, and adjacent cortex, the lobe is separated from the rest of the brain by a large cut. Generalized weekly seizures were all but eliminated and partial daily seizures reduced to only a few per day.

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