BLG 151 Chapter Notes - Chapter 15: Light-Independent Reactions, Anaplerotic Reactions, Carbonic Anhydrase
19 Jan 2018
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Document Summary
Amycolatopsis mjm2582, a newly discovered actinomycete bacterium: produces dozens of different secondary products like the antibiotic risocetin. Anabolism requires: essential elements: c, h, o, n and others, reduction: by reducing agents such as nadph, energy: by coupling reaction to atp hydrolysis, nadph oxidation, or ion flow down a transmembrane concentration gradient. Many substrates for biosynthesis arise form glycolysis and the tca cycle. Note: glucose catabolism and tca cycle are both reversible processes. Succinyl-coa molecules = used to make several amino acids and vitamin b12. Glycerol 3-phosphate = used to make the glyceride backbone of lipids. Pyruvate = used to make the backbone of amino acids with aliphatic side chains. Enzymes couple reactions that synthesize molecules to reactions that release energy. There is a high genomic and energetic cost for biosynthesis reactions. This cost has led to microbes to evolve strategies to control these costs so they do not spend so much energy making molecules.
