PAT 20A/B Chapter Notes - Chapter 26: Myocardial Infarction, Coronary Artery Disease, Ejection Fraction
18 Jan 2017
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Document Summary
Perfusion of tissues depends on the pumping ability of the heart, the vascular system to transport blood to cells and heart, sufficient blood to fill the circulatory system and tissues ability to use oxygen and nutrients from blood. Results from functional or structural disorder of the heart impairing ability to fill with or eject blood. Usually results from hypertension and coronary artery disease. Mortality rate is high at an 8 year survival rate of 15% Preload: reflects the volume of the ventricle at the end of diastole; it is the volume of blood stretching the heart muscle at the end of diastole. Afterload: represents the force that the contracting heart muscle must generate to eject blood from the heart; resistance and wall tension contribute to the afterload. Refers to the contractile performance of the heart. Represents the ability of the contractile elements (actin and myosin) Interaction between actin and myosin requires energy from breakdown of atp and presence of.
