PAT 20A/B Chapter Notes - Chapter 29: Theophylline, Elastin, Afterload
31 Jan 2017
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Document Summary
Chapter 29: disorders of ventilation and gas exchange (pp. Caused by disorders that limit inspiratory or expiratory airflow or both. Bronchial asthma rep-resents an acute and reversible form of airway disease caused by narrowing of airways due to bronchospasm, inflammation, and increased airway secretions, that restricts air entry and may obstruct expiratory airflow. Chronic airway disorders include chronic obstructive pulmonary disease, bronchiectasis, and cystic fibrosis. Classic symptoms include: wheezing, shortness of breath, chest tightness, and cough. Prevention of inflammatory and immune responses is important to prevent long term and permanent damage and structural changes. Intrinsic asthma: family history or positive response to serologic test to common allergens. Extrinsic asthma: hypersensitive (atopic) allergic response to external antigen (immune- related) Asthma is a hypersensitive response to stimuli. Inflammatory cells are triggered which leads to inflammation and causes damage to bronchial epithelium thus epithelial cells are activated causing injury to bronchi.
