BIOL 2050 Chapter 10: Module 8 - Transcription

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4 Mar 2017
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10. 1 rna, a single strand of ribonucleotides, participates in a variety of cellular function. The structure of rna polymer made of nucleotides joined together by phosphodiester bonds differences bw rna and dna: rna contains ribose sugars. Dna contains deoxyribose sugars: rna is degraded rapidly under alkaline conditions bc of the free. Oh on the 2" carbon of the ribose sugar. Dna lacks this free oh and so it is more stable: rna has uracil. Dna consists of 2 polynucleotide strands joined by h bonding bw complementary bases. Classes of rna ribosomal rna (rrna: makes up the ribosome. Messenger rna (mrna) carries the coding instructions for polypeptide chains from dna to the ribosome: after attaching to a ribosome, an mrna molecule specifies the sequence of the amino acids. Micrornas (mirnas) and small interfering rnas (sirnas) carry out rna interference (rnai: process in which these small rna molecules help trigger the degradation of mrna or inhibit its translation into protein.

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