KNES 437 Chapter Notes - Chapter 2: Obstructive Lung Disease, Gestational Diabetes, Thrifty Phenotype
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Developmental origins of health span and life span: a mini-review. Starting a pregnancy overweight/obese is also an issue! Low birth weight is probably not the cause of increased risks of developing issues later in life, but probably a co- factor along with other mechanisms that were set in place due to parental effects. [38] found those who were thin at birth (low birth weight), but experienced catch-up growth had increased cvd morbidity as adults. Parental longevity and age at conception, telomere length, and season of birth. Telomere length: high maternal pre-pregnancy bmi independently led to shorter telomere length in newborn offspring (measured in placenta and cord blood) [57]. A study in a homogenous amish population found that paternal telomere length was associated with telomere length in offspring, and paternal life span was correlated with telomere length in female offspring [58].