KNES 437 Chapter Notes - Chapter 12: Natural Killer Cell, Sleep Deprivation, Circadian Rhythm
6 Mar 2020
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Introduction: a classic paradigm in exercise immunology is that an open window of immunodepression can occur during recovery from intense exercise. In particular, this paradigm proposes that after intense exercise, some immune variables (e. g. , lymphocyte and natural killer cell numbers and antibody production) transiently decrease below pre-exercise levels. Intense training over an extended period without sufficient balance between training and recovery may lead to. Nonfunctional overreaching : this condition is typically characterized by persistent fatigue, performance decrement, muscle soreness, and psychological and hormonal disturbances that can last for weeks or months, overtraining syndrome , aka insufficient recovery. Chronic sleep disturbance (12: nights, 50% sleep loss) increases the plasma inflammation markers c-reactive protein and il-6 (38). However, intervening daytime naps can counter this apparent inflammatory response: people who experience poor-quality sleep and/or regular sleep deprivation also have a 4$ 5 times greater risk of developing the common cold.
