BIOL 1080 Chapter Notes - Chapter Lecture 6 Readings: Hydrophile, Cell Membrane, Cytosol

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Lecture 6 reading pg. 115-130 part 3a (i) continued. Amines: synthesized in the cytosol by enzyme-catalyzed reactions, following synthesis they are packaged into cytosolic vesicles where they are stored until their release si triggered. Note the synthesis of norepinephrine and epinephrine is complete in the vesicle, where dopamine and pnmt (enzymes) are located. Golgi apparatus: in golgi it is packaged into secretory vesicle in which more amino acids cleave off to create the nal product, a peptide, release occurs by exocytosis. Steroids: synthesized from cholesterol in a series of reaction catalyzed by enzymes in the. Ser or mitochondria shown on diagram on 117. Once released a messenger needs to nd and bind to the receptor on the target cell. Most messengers quickly degrade in the interstitial uid and become inactive, but hormones are transported in the blood often in dissolved form (hydrophilic) or bound to carrier proteins (hydrophobic)

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