BIOM 3200 Chapter Notes - Chapter all: Pituitary Pars Intermedia Dysfunction, Zona Fasciculata, Zona Glomerulosa

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Endocrine: claude bernard originator of modern physiology, homeostasis: remaining relative internal consistency, despite changing external environment. In a negative feedback loop, sensors send information to an integrating center (brain, spinal cord, endocrine glands). The integrating center uses this information to direct a response of an effector (muscles or glands). An increase or decrease of effector response helps maintain the set point of homeostasis. In a positive feedback loop, the action of the effectors amplifies the changes that stimulate the sensors. Examples include blood clotting, estrogen stimulating release of lh, and oxytocin stimulating contraction of the uterus during childbirth. Inactive hormones that must change structure to be active are prehormones. Cretinism: also, due to maternal hypothyroidism or iodine deficient diet, can be treated with thyroxine in first month, hypothyroidism will also see low levels of t3 and t4, can also cause goiters, hyperthyroidism can cause.

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