MBG 2040 Chapter 12: Chapter 12 notes
9 Mar 2016
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Chapter 12 translation and the genetic code. Caused by a single amino acid change. Amino acids are the building blocks of protein. Amino acids: free amino group, free carboxyl group, side chain (r) Amino acids are joined by peptide bonds: carboxyl group of one amino acids is covalently linked to amino group of another. *recall: transcription and translation are tightly coupled in prokaryotes (see. Ribosomes: made of polypeptides and rna molecules. Soluble proteins (translation factors) involved in polypeptide chain initiation, elongation, and termination. Divided into a large and small subunit. Rna machine with key rna roles including formation of peptide bonds. Mature ribosomal rna (rrna) molecules are processed from much larger rrna transcripts than rna found in ribosomes. The site of eukaryotic rrna synthesis and ribosome assembly. A region in the nucleus designated by chromosome interactions, as opposed to a compartment separated by a membrane. Adaptors between amino acids and the codons in mrna molecules.
