MBG 3080 Chapter Notes - Chapter 7: Genetic Linkage, Okazaki Fragments, Concatemer
9 Dec 2013
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I have the third edition textbook, so references to figures may vary if you have the 4th ed. Chapter 7: lytic bacteriophages: development, genetics, and generalized transduction. Bacteriophages (phages) viruses that infect bacteria most abundant biological entity not a living organism but a nucleic acid (dna or rna) wrapped in a protein and/or membrane coat for protection. To start infection, phage attaches to specific receptor on cell surface, it then injects its dna into cell, where transcription of rna (usually by host rna polymerase) begins almost immediately. Not all genes transcribed to mrna when dna first enters cell, only some genes have promoters that mimic those of the host dna and so are recognized by host rna polymerase. These genes are called early genes, and they encode for enzymes involved in dna synthesis (i. e. dna polymerase, primase, dna ligase, and helicase). With the help of these enzymes, the phage. Dna begins to replicate and copies accumulate in cell.
