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MICR 3230 (19)
Chapter

Chp9 The T-Cell Receptor

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Department
Microbiology
Course
MICR 3230
Professor
Azad Kaushik
Semester
Fall

Description
The TCell Receptor Chapter 9 Summarymost TCRs react with processed antigen bound to a selfMHC molecule rather than soluble antigenisolated by means of clonotypic monoclonal antibodiesheterodimers consisting of anorchain certainreceptors recognize antigens not processed and presented with MHCmembranebound TCRs organized into variable and constant domainsdomains similar to those of Igv region has hypervariable regionsTCR germline DNA organized into multigene families corresponding to the chains Mechanisms of TCR diversity similar to Ig although NO somatic hypermutationTCR closely associated with CD3 compl
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