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Chapter 3

NUTR 2050 Chapter 3: Chapter 3

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NUTR 2050
Dalia El Khoury

Wednesday, March 1, 2017 Chapter 3: Preconception Nutrition Continued Weight Status And Fertility obesity, body fat distribution, and fertility • overweight impacts fertility and pregnancy in women with metabolic abnormalities such as, insulin resistance (when more insulin is required to transport a given amount of glucose into cells as cell membranes have reduced sensitivity to insulin) and chronic inflammation • absence of high levels of intra-abdominal fat reduces poor health outcomes • obesity marked by excess intra-abdominal fat is related to insulin resistance, elevated levels of insulin, chronic inflammation, oxidative stress, and metabolic syndrome (cluster of abnormal metabolic and health indicators and is characterized by insulin resistance, abdominal obesity, high blood pressure and triglycerides levels, low levels of HDL cholesterol, and impaired glucose tolerance) • in women, elevated blood insulin levels reduce sex hormone binding globulin (SHBG), which prompts the ovaries to increase production of testosterone, and excess testoste
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