PSYC 2410 Chapter Notes - Chapter 4: Propranolol, Glutamate Transporter, Grin2B

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Cell membrane: semi-permeable barrier: made of double layer of phospholipids which have a polar hydrophilic head and a hydrophobic body (nonpolar). Nonpolar areas form a hydrophobic region between the hydrophilic head. At body temps the interior of the bilayer is fluid: cholesterol, give rigidity to cell membrane while remaining a fluid environment. Glycolipid: sugar groups attached to their heads point into the extracellular space. Transmembrane or integral proteins: across the entire bilayer. Signal proteins: involved in communication b/w cells. Channel proteins: allows exchange of specific substances b/w inside and outside of the cell. Peripheral membrane proteins: either on the outside or inside, close association with the bilayer and with integral or transmembrane proteins. Can help the function of transmembrane proteins, open/close. Transmembrane traffic: lipids of membranes form a barrier to hydrophilic molecules, but need transportation across it: diffusion: movement of substance (liquid or gas) along a concentration gradient (high low).

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