PSYC 3850 Chapter Notes - Chapter 6: Intrauterine Growth Restriction, Hemolytic Disease Of The Newborn, Intellectual Disability

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O occur when some abnormality emerges in number or configuration of chromosomes in the body: new kind of abnormal condition involves extra chromosomes, such as 3 chromosomes in position 21 or 2 or more x- or. This can also involve abnormally shaped chromosomes: turner syndrome (gonadal aplasia) when 45 chromosomes present with only single x-chromosome. Characteristics lateral upward slope of eyes, protruding tongue, short nose, flattened head, short, stocky build. Trisomy extra chromosome occurs in group g, most common and has definite correlation with maternal age. Translocation occurs in 8% affected infants born to mothers < 30 and 2% in mothers > 30. Some of chromosomal material of 21st pair in group g becomes attached to chromosome of 15th pair in group d, causing extra long chromosome. Parent can either be carrier or can occur by chance chromosomal error. Birth weight (bw) and gestational age (ga) postterm.

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