PSYCH261 Chapter 7: Psychopharmacology
6 Sep 2017
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Document Summary
Psychoparmacology: study of the effects of drugs on the nervous system/behavior. Sites of action: where the drug effects in the body. Pharmacokinetics: process of drug absorption, distribution, metabolism and excretion. Drug exogeneous chemical not necessary for normal cellular functioning that alters functions in the body. Drug effectiveness: drugs excreted by kidneys, liver helps enzymes deactivate drugs, some enzymes are already in blood, in some cases enzymes can make the drug more active. Affinity readiness with which two molecules join together. Therapeutic index ratio that produces desired effect 50% of the time and the does that produces toxic effects 50% of the time. Tolerance decrease in effectiveness of drug that is administered repeatedly. Sensitization increase in effectiveness for a repeatedly administered drug. With-drawl symptom appearance of symptoms opposite to those produced by a drug when the rug is administered repeatedly and is no longer taken or the effects are no longer felt.
