PSYCH261 Chapter Notes - Chapter 11: Benzodiazepine, Thalamus, Anxiolytic

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Module 11.2 Attack and Escape Behaviours
Eotio is ebodied – what you are doing affects how you feel
Effects of hormones
- Testosterone
o Males aggressive behaviour depends on testosterone, which is highest for adult
males in the reproductive season
o Those with higher testosterone levels tend on average to be more aggressive
o Aggression depends on the ratio of testosterone to cortisol, not testosterone
alone
- Serotonin
o Serotonin also tends to inhibit violent impulses, so impulsive aggression is
highest when testosterone levels are high and both cortisol and serotonin are
low
Turnover: the amount that neurons released and replaced
Researchers measure serotonin turnover by the [] of 5-hydroxyindoleacetic acid (5-HIAA),
serotoi’s ai etabolite, i the cerebrospinal fluid (CSF)
- The more 5-HIAA, the more serotonin has been released and presumably resynthesized
Genes influence violent behavior in many ways, including autonomic arousal
- People with lower than average autonomic arousal tend to be more aggressive,
probably because they react less strongly to fear of the consequences
- Low serotonin activity is weakly associated with increased aggression, but the form of
the MAO gene that strongly breaks down serotonin links to less aggression, and only for
people with a history of childhood maltreatment
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Document Summary

E(cid:373)otio(cid:374) is (cid:862)e(cid:373)bodied(cid:863) what you are doing affects how you feel. Serotonin: serotonin also tends to inhibit violent impulses, so impulsive aggression is highest when testosterone levels are high and both cortisol and serotonin are low. Turnover: the amount that neurons released and replaced. Researchers measure serotonin turnover by the [] of 5-hydroxyindoleacetic acid (5-hiaa), seroto(cid:374)i(cid:374)"s (cid:373)ai(cid:374) (cid:373)etabolite, i(cid:374) the cerebrospinal fluid (csf) The more 5-hiaa, the more serotonin has been released and presumably resynthesized. Genes influence violent behavior in many ways, including autonomic arousal. People with lower than average autonomic arousal tend to be more aggressive, probably because they react less strongly to fear of the consequences. Low serotonin activity is weakly associated with increased aggression, but the form of the mao gene that strongly breaks down serotonin links to less aggression, and only for people with a history of childhood maltreatment.

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