PSYCH261 Chapter Notes - Chapter 3.3: Transcranial Magnetic Stimulation, Karl Deisseroth, Frontal Lobe

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Psych 261 - module 3. 3 - research methods. Broca"s area: loss of speech due to damage in left frontal cortex. Brain damage: can produce inability to recognize faces, perceive motion, shift of attention to right side of body and world, memory impairments, etc. Carefully localized damage in lab. animals for research: Ablation: removal of brain area, generally with a surgical knife. Make a lesion (use stereotaxic instrument for precise placement of electrodes in the brain) Drills a hole in brain, insert electrode, damages that area. Produces a sham lesion to check if the damage was only caused by anesthetizing the animal. ^^ a crude technique, damages axons passing by and neurons in area. Gene-knockout approach: directs a mutation to a gene that is important for one type of cell, transmitter, or receptor. Ex; transcranial magnetic stimulation (tms): application of magnetic stimulation to a portion of scalp, inactivates neurons in narrow area below magnet.

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