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BIOL 112 (145)
Chapter 4

Bio Chapter 4 Notes.docx

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School
University of British Columbia
Department
Biology
Course
BIOL 112
Professor
Karen Smith
Semester
Winter

Description
Chapter 4 Notes 4.1 What is a Nucleic Acid? - Nucleic Acids: - polymers made of nucleotides instead of amino acid monomers like proteins - Nucleotides: consist of three parts: 1. A sugar: organic compound with a carboxyl group and several OH- groups - Two kinds of sugars: Ribose (OH on 2’) Deoxyribose (H on 2’) 2. A nitrogenous base: attached at 1’ of sugar Pyrimidines: Cytosine, Uracil, Thymine Purines: Guanine, Adenine 3. Phosphate group: attached at 4’ of sugar - Polymerization: nucleic acids form when nucleotides polymerize Phosphodiester linkage: rxns = bond between phosphate group of one nucleotide and the hydroxyl group on the sugar of another nucleotide If the sugar is ribose = RNA, deoxyribose (always 5’  3’) Process needs energy, free energy of nucleotide monomers add 2 phosphate groups to ribonucleotides o
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