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BIOL 336 Chapter Notes -Genetic Drift, Blood Orange

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jadepig631
26 Jan 2013
School
UBC
Department
Biology
Course
BIOL 336
Professor
Greg Bole

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Document Summary

60463080: selection acts directly on phenotypes, as it is phenotypic variation that creates differences between survival rates and reproductive success of individuals. However, phenotypes are a result of genotypes interacting with the environment; and genotypes are combinations of alleles. Phenotypes are usually a combination of different alleles and their interactions with the environment. In haploid organisms, it is possible that a single allele may be responsible for a particular phenotype if it is the only other allele in a population of haploid organisms that shows a difference in phenotype. Since we set the population size to be infinite, we eliminate the probability of genetic drift occurring. In run 1, w11 is 1. 22 so has an advantage over. Therefore the number of a1 alleles is low in the beginning and most likely found in heterozygotes. Allele a1 rapidly increases once drift or some mechanism increases their frequency slightly, and then selection overtakes the curve.

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Related Questions

Expression vectors inprokaryotes do not make functional eukaryotic gene products inbacteria very well because

Answer Not sure which one ?!

· the codon sequence for prokaryotes is differentthan the codon sequence in eukaryotes

· there are no disulfide bridges formed in proteinsnormally made in prokaryotes

· prokaryotic expression vectors cannot translateeukarytic sequences

· eukaryotic genes have introns, and prokaryotesdon't

· eukaryotic genes have exons and prokaryotesdon't


I create a knockout mouseusing the agouti/black fur system \. When I cross the agoutioffspring of the originally engineered mouse, I find a ratio of 2agouti mice to 1 black furred mouse. What is the bestexplanation?

Answer not sure which one?!

· The gene knocked out was recessive.

· The gene knocked out was dominant.

· The gene knocked out was a lethalgene.

· The knockput was integrated into a random spot,and did not knockput the original gene.

A restriction enzyme cuts DNAand leaves the following end

xxCTGCA
xxG

Which of the following could be the sequence of the correspondingend of the other end of the cut DNA?

Answer

· xxG
xxCTGCA

· xxC
xxGTGCA

· xxCCGAT
xxG

· xxGGCTA
xxC


An SNP always occurs dueto

Answer

· a one base-pair change.

· a three base-pair change.

· a single restriction site change.

· a single amino acid change.

· None of these.


I PCR out a mutated gene in apatient with Lisenbee chorea (the inability to dance in acoordinated fashion) and I compare it to another patient with thatsame disease phenotype. One subject had a mutation on chromosome 4,and the other subject couldn't rock it because of a mutation onchromosome 5. This is an exampe of

Answer

· pleitropy

· locus heterogeneity

· allelic heterogeneity

· dominant negative mutation

· penetrance

In his experiments, Mendelnoted that when two traits are involved in a genetic cross, theyare inherited independently of each other. Though Mendel didn'tknow about chromosomes, this still holds true (mostly)because

Answer

· genes on the same chromosome are often mixedthrough meiotic crossover during the formation ofgametes.

· variant alleles of the same gene do not interferewith the phenotypic expression of the gentoype in different geneticloci.

· most higher organisms are diploid, making only twoalleles available for every genetic locus, and there is a 50/50chance of geting either allele from a single parent.

· expression of phenotypes can vary from thegenotypes because of encironmantal influences.

· chromosomes often recombine

Anticipation is caused by amutation that increases in expressivity over subsequentgenerations.

Answer

· True

· False

Question 44

I have a genotype that shouldproduce a specific phenotype, but some of the individuals with thegenotype do not demonstrate any evidence of the phenotype. I wouldconsider this an example of

Answer

· allelic heterogeneity.

· locus heterogeneity.

· penetrance.

· expressitivity.

· sheer luck.

Question

Which of the following doesnot occur during the PCR reactions?

Answer

· Changes in the reaction temperature by athermocycler

· Denaturation at high temperatures

· Synthesis of oligonucleotide primers

· Extension of primers by DNA polymerase

· Annealing of oligonucleotide primers

Question

DNA markers, or variantnon-coding regions of DNA, are DNA polymorphisms that are usefulfor genetic mapping.

Answer

· True

· False

A mosaic is an organismwith

Answer

· multiple genotypes within one organism

· multiple alleles within one genotype

· more than one color of fur

· transgenes added to the zygote beforedevelopement

· a wt phenotype but a mutated genotype

Question

Genotype causesphenotype.

Answer

· No, gentoype just influences phenotype.

· Yes, genotype is the DNA sequence that createsphenotype.

Question

A true genetic chimera can becreated by

Answer

· mutating a gene early on in the development of anorganism resulting in different alleles being present in theadult

· multiple fertilized eggs or zygotes fusing to formone embryo

· adding a transgene to the genome of an organismduring fetal development only

· adding cells of a different species to an adultorganism

· adding a transgene to the genome of an animal atany stage in development

Question

The ABO blood group can bestbe explained by the concept of _______.

Answer

· dominant traits

· recessive traits

· allelic heterogeneity

· locus heterogeneity

· vampirism

If a loss of functionmutation creates a dominant phenotype, it may be becauseof

Answer

· haploinsufficiency

· penetrance

· expressivity

· allelic heterogeneity

· locus heterogeneity

Please select the best matchfor each.

Answer

· PCR: Technique used to generatecopies of a DNA fragment

· Southern blot : Screeningprocedure used to assay DNA fragments

· RFLPs : DNA fragments generatedby restriction enzymes that vary in length betweenindividuals

· Northern blot : Screeningprocedure used to assay mRNA fragments

· Electrophoresis Movement ofmacromolecules in an electrical field

Answer

A.

Screening procedure used toassay DNA fragments

B.

Movement ofmacromolecules in an electrical field

C.

Screening procedure used toassay mRNA fragments

D.

DNA fragments generated byrestriction enzymes that vary in length betweenindividuals

E.

Technique used to generatecopies of a DNA fragment

A gene mutates, and theprotein produced has a novel way of interacting with the cell, andcreates a new phenotype because of this new functionality. This iscalled

Answer

· pleitropy

· locus heterogeneity

· allelic heterogeneity

· dominant negative mutation

· gain of function dominant mutation

Question 62

Mutations in the somaticchromosomes may be inherited by the next generation.

Answer

· True

· False


A degenerate PCR primer withmany variant sequences must be used to make multiple copies of agene

Answer

· if only the protein sequence of the gene productis known to construct the primers

· if the DNA you are using is cDNA to constructthe primers

· if the DNA you are using is genomic DNA to becopied

· if the DNA you are trying to copy iscDNA

· if the vector is prokaryotic and the transformedcell is eukarytotic

Question

Please select the best matchfor each term.

Answer

· Restriction enzyme


· PCR C

· Plasmid

· YAC A

· Dideoxynucleotide

Answer

A.

Endonuclease isolated frombacteria

B.

Eukaryotic cloningvector

C.

Method for amplification ofDNA sequences

D.

Small circular fragment ofDNA

E.

Molecule used in DNAsequencing

Question

A couple goes on MauryPovitch, and the results are in: you are not the father. But noother man impregnated the female (granted, unlikely for a MauryPovitch guest, but work with me here) and he must be the father.DNA analysis claims otherwise, though the child definitely wasmom's (poor thing). What may be going on here?

Answer

· the child is parthenogenic because the motheractually impregnated herself like a shark, and the child's DNA isall mom's

· the child had a mutation that changed the genethat is used to trace paternity

· the child is a mosaic because he is actually a setof twins fused early during fetal development, and therefore camefrom 2 eggs and 2 sperm

· the dad may have germ-line mosaicism, meaning thatthe genotype of his sperm is different from his somaticgenotype

· mitochondrial DNA only comes from mom, so there isno way to tell whobthe baby's father is




1. Characters that show a continuous range of variation, such as height and eye color, usually are controlled:

a. by a single gene with two alleles that are codominant.
b. by many genes with an additive effect.
c. by epistatic interactions between two genes.
d. mainly by the environment, with only a small genetic component.

2. In humans, red-green colorblindness is inherited as a sex-linked recessive trait. In order for a woman to be red-green colorblind, which of the following statements must be true.

a. Her mother must be red-green colorblind.
b. All of her brothers must be red-green colorblind.
c. Her father must be red-green colorblind.
d. All of the above statements must be true if a woman is red-green colorblind.

3. The x-ray crystallography data collected by Rosalind Franklin suggested to Watson and Crick that the:

a. structure of DNA is a double helix.
b. two strands of the DNA molecule are joined by hydrogen bonds between the bases.
c. four bases within DNA pair in a specific way.
d. two strands of the DNA molecule are joined by covalent bonds between the bases.

4. In the genetic code, _________ one amino acid.

a. one nucleotide specifies
b. two nucleotides specify
c. three nucleotides specify
d. four nucleotides specify

5. During Meiosis I, a homologous pair of chromosomes may not separate, resulting in daughter cells that have extra chromosomes or are missing chromosomes. This can lead to genetic disorders, including Down Syndrome. This phenomenon is called:

a. independent assortment.
b. nondisjunction.
c. segregation.
d. crossing over.

6. You are a human geneticist studying the incidence of retinitis pigmentosa in the residents of Tristan de Cunha, a group of small islands in the middle of the southern Atlantic Ocean. The allele for retinitis pigmentosa, which causes a form of blindness, is inherited as an autosomal recessive. You have determined that the frequency of this allele (r) in the population is 0.4 (40%). Using the principles of the Hardy-Weinberg rule, you would estimate the frequency of individuals who are heterozygous for this allele (Rr) in the population to be:

a. 0.16 (16%)
b. 0.24 (24%)
c. 0.36 (36%)
d. 0.48 (48%)

7. Natural selection acts at the level of the:

a. phenotype.
b. gene.
c. population.
d. nucleotide.

8. You are working with pea plants, trying to recreate the experiments that Mendel performed. You are doing a dihybrid cross with a plant that is heterozygous for both seed shape and seed color, with the genotype RrYy. Which allelic combinations would you expect to find in the gametes produced by this plant?

a. This plant would produce only RY and ry gametes.
b. This plant would produce only RrYy gametes.
c. This plant would produce RY, Ry, rY, and ry gametes.
d. You cannot determine which gametes this plant can produce without knowing the genotypes of its parents.

9. Biochemist Erwin Chargaff found that in DNA there is a special relationship between the four bases that we now call Chargaff's rule. His observation was that, in an organism's genome the:

a. percentage of A nucleotides = the percentage of T nucleotides, and the percentage of C nucleotides = the percentage of G nucleotides.
b. four bases all occur in an equal frequency (25%) within each organism.
c. percentage of A nucleotides = the percentage of G nucleotides, and the percentage of C nucleotides = the percentage of T nucleotides.
d. genetic material is composed of proteins, not DNA.

10. During DNA replication:

a. each strand of the double helix acts as a template for the synthesis of a new strand.
b. the enzyme DNA polymerase adds nucleotides to the strand being synthesized.
c. the bases A,C,G and T are required.
d. All of the above are true of DNA replication.

11. During translation, amino acids are joined by peptide bonds to make polypeptides. The formation of these peptide bonds is catalyzed by:

a. DNA.
b. mRNA.
c. tRNA.
d. rRNA.

12. If an allele (R) at a gene with two alleles shows complete dominance, individuals with the genotypes ______ will have the same phenotype.

a. RR and rr.
b. RR and Rr
c. Rr and rr
d. Each of the three possible genotypes will have a different phenotype.

As temperatures in an African savanna increase and rainfall decreases, it would most likely change into

tiaga

desert

tropical rainforest

temperate forest

What is imprinting? Give an example.

fixed assocation, such as hatching ducks recognizing the first animal they see as their mother

a learned behavior, such as a wasp circling during a search for food, so that it can return to its nest

alteration of instinct, such as a spider changing the type of web it weaves depending upon the environment

Opportunistic species

provide extensive care for their offspring

produce many offspring

reproduce later in life

What are the five agents of microevolution?

gamete production; mating; fertilization; caring for offspring; formation of herds

photosynthesis; respiration; mitosis; meiosis; fertilization

mutation; gene flow; nonrandom mating; genetic drift; natural selection

Microevolution is

new species

minor extinction of species

changes in allele frequency in a population

Which of the following is does not help defend against predators?

Toxins made by plants that injure caterpillars feeding on the plant

The large eyespots on a moth's wing that can startle a hungry bird

Thorns on a plant

Many plants have brightly colored fruit and flowers

Humans have a favored birth weight, neither too small nor too large. This is

stabilizing selection

disruptive selection

artificial selection

directional selection

What is a keystone species?

the first organism that populates an area

an organism upon which the entire ecosystem depends

the first fossils found in the earliest rock strata

As temperatures in the Arctic warm, which of the following changes may occur?

Tundra will be replaced by taiga

Taiga will be replaced by tundra

Temperate forest will be replaced by taiga

Tundra will be replaced by desert

Taiga will be replaced by temperate rain forest

What is desertification?

restoration of vegetation and water to deserts

areas adjacent to deserts also become deserts

abandonment of a habitat by animals

Evolution occurs at the level of

individuals

populations

communities

The maximum population that the environment can support is called the

biotic potential

environmental resistance

carrying capacity

replacement reproduction

demographic transition

A population with relatively more pre-reproductive individuals is common in _____-developed countries

more

less

Endangered species sometimes breed in captivity. Why are such species endangered in the wild?

Their population density is too high

Loss of habitat

Their environment is polluted

Abiotic components of an ecosystem include

only animal life

only plant life

living components only

nonliving components only

both living and nonliving components

Carbon returns to the atmosphere

as carbon dioxide

from respiration of plants

by the burning of fossil fuels

from respiration of animals

All of the answer choices are correct

Why does the Tropical Rain Forest contain an abundance of antibiotic compounds?

The area is crowded, leading to random production of useful compounds

The area is wet. plants had to develop resistance to fungi and bacterial infections

There is a great diversity of plants, leading to random production of useful compounds

The carrying capacity of the environment for a species is determined by

the reproductive rate of the organism

the number of organisms of that species

the state and national wildlife laws pertaining to that species

a complex

the limited productivity of the environment and the environmental resistance to the biotic potential of the organism

An introduced species that breeds and spreads is

resourceful

harmful

native

dominant

invasive

What is disruptive selection?

environmental influences that select against change

environmental influences that promote one phenotype versus all others

environmental influences that promote two or more phenotypes versus all others

Natural selection acts on

individuals

populations

communities

Two populations of birds live in the same area but have different sleep/wake cycles. This is

behavorial isolation

mechanical isolation

geographical isolation

temporal isolation

An insect that resembles the face of a snake avoids predation by

camouflage

warning coloration

mimicry

chemical defense

mutualism

Unselfish acts that help others in a group so that they increase their chances of surviving and reproducing is called

imprinting

mimicry

altruism

learning

instinct

If an environment changes rapidly, organisms with ____ will be more likely to survive and reproduce.

the correct allele frequency

existing neutral mutations

existing beneficial mutations

How did geology influence Darwin’s thoughts?

It demonstrated that the earth was very old, therefore there was enough time for species to evolve

it demonstrated that all continents were similar

it demonstrated the presence of many fossils

The founder effect occurs when

large groups of individuals leave their home population and establish new settlements, mating only among themselves

many members of a population die, resulting in a great loss of genetic diversity

many members of a population reproduce causing too much genetic diversity within the population

small groups of individuals leave their home population and establish new settlements, mating only among themselves.

The greenhouse effect is due to high atmospheric

Nitrogen

Ammonia

Carbon monoxide

Carbon dioxide

Oxygen

What are the Reproductive Barriers that keep species separate?

lack of food; lack of habitat; lack of potential mates; lack of nesting sites; lack of genetic variation

mountains; canyons; glaciers; bodies of water (for terrestrial animals); areas of land (for aquatic animals)

habitat isolation; temporal isolation; behavioral isolation; mechanical isolation; gamete isolation

What is directional selection?

environmental influences that select against change

environmental influences that promote one phenotype versus all others

environmental influences that promote two or more phenotypes versus all others

Which of the following is correct when describing a predator-prey cycle?

A decline in the numbers of predators causes a decline in the number of prey

A decline in the numbers of prey causes a decline in the number of predators

An increase in the number of predators triggers an increase in the number of prey

An up-and-down cycle will be seen for the prey animal

A seasonal die-off that will occur without the other species present

Why are top-level predators (lions, eagles, humans) so rare in a community?

Only a small amount of the energy is passed from one trophic level to the next

They do not breed as fast as other animals

Because of predation by higher predators

It is difficult for them to learn how to capture prey

Their job is to keep the population size of other animals in check

Alleles conferring bright color to male guppies are common because

they make males less visible to predators

they help males identify each other

they are preferred by females

Organisms that obtain their energy from producers or other consumers are

autotroph

heterotroph

producer

autotroph and producer

heterotroph and producer

What is the environmental impact of strip mining?

lack of trees exposes the surface of the earth, promoting runoff and loss of adjacent trees

removal of minerals from the soil hampers growth of vegetation

it causes a potential increase in volcanic activity

Two populations of squirrels are separated by a mountain range and would not be capable of interbreeding. This is an example of:

behavorial isolation

mechanical isolation

geographical isolation

temporal isolation

What is a danger of overfishing?

humans will become dependent upon fish

selection for smarter fish that can avoid being caught

driving the population back into the lag phase

What is meant by prezygotic versus postzygotic speciation mechanisms?

before versus after formation of a zygote

before versus after meiosis

before versus after gamete formation

The relatively short term changes in allele frequencies within a species or population is

artificial selection

microevolution.

speciation

macroevolution

Avoidance of a location with predators is the result of

imprinting

mimicry

altruism

learning

instinct

What is the difference between Density-Dependent and Density-Independent Factors on populations?

density-dependent factors exert a greater influence when there are more individuals; density-independent exerts the same influence on all individuals regardless of their number

density-dependent factors exert a greater influence on larger, more dense individuals; density-independent factors exert the same impact on individuals of all size

density-dependent factors exert the same influence on all individuals regardless of their number; density-independent factors exert a greater influence when there are more individuals regardless of their number

All of the organisms in a given location or area is termed a

peer group

flock

community

population

herd

The concentration of the pesticide DDT would be highest in

a minnow

a mosquito larva

a seagull

plankton

algae

Our biosphere is

the Earth

the atmosphere

the ocean

land on Earth

fresh and salt water

What is meant by “carrying capacity”?

the amount of food produced in an ecosystem

the extent of energy required to maintain an ecosystem

the number of individuals that can be supported by an ecosystem

Species living on another is

resource partitioning

coevolution

symbiosis

predation

niche sharing

One species feeding on another is

competition

a community

an ecosystem

predation

symbiosis

Populations of different species interacting with one another in a natural environment is called

competition

a community

a biome

predation

symbiosis

Which of the following is not a biogeochemical cycle?

ATP cycle

water cycle

carbon cycle

phosphorus cycle

nitrogen cycle

Horses became larger and faster to escape predators. This is

stabilizing selection

disruptive selection

artificial selection

directional selection