PSYC 2050U Chapter Notes - Chapter 4: Substantia Nigra, Metabotropic Receptor, Neuromuscular Junction
Document Summary
Reuptake of transmitter relies on specialized proteins called transporters that bind molecules of nt and take them back up into the pre-synaptic terminal. Ionotropic receptors ion channels that open or close when a neurotransmitter binds to them: can change the membrane potential of the postsynaptic cell. Metabotropic receptor does not contain ion channels but uses second messenger systems to open nearby ion channels or other cellular expressions: affect gene expression, production of receptors and signalling chemicals. Amino acid nt & peptide nt single amino acid molecules or on short chains of amino acids. Amine nt ach, dopamine, and serotonin. Gas nt soluble gases that diffuse through neurons: nitric oxide and carbon monoxide. Nt systems form a complex array in the brain. Most common in the brain are amino acids. Glutamate the most common excitatory nt in the brain: ndma receptors memory formation. Nitrogen-containing compounds related to ammonia, derived from an amino acid.
