ANP 1106 Chapter Notes - Chapter 6: Intramembranous Ossification, Biomineralization, Osteoid

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The human skeleton is initially made up of cartilages and fibrous membranes and are soon replaced by bone. The remaining cartilage is found in regions where flexible skeletal tissue is needed. Made up of some variety of cartilage tissue. Consists primarily of water (up to 80%) which allows it to compress and return to its original shape (i. e. : gives it resilience) Surrounded by a layer of dense irregular connective tissue known as the perichondrium. This acts as a girdle to resist outward expansion when cartilage is compressed. Contains blood vessels that allow nutrients to diffuse through the matrix to reach the cartilage cells. Hyaline, elastic, and fibrocartilage make up the 3 types of cartilage tissue in the body. Cartilage cells are known as chondrocytes, and are encased in small cavities called lacunae within an extracellular matrix containing a jellylike ground substance and fibres. Chondroblasts are immature cartilage cells and actively form cartilage; have a high metabolic rate.

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