Textbook Notes (270,000)
CA (160,000)
UOttawa (6,000)
ANP (200)
Chapter 10

ANP 1106 Chapter Notes - Chapter 10: Retinal Ganglion Cell, Crista Ampullaris, Pupillary Light Reflex


Department
Anatomy and Physiology
Course Code
ANP 1106
Professor
Jacqueline Carnegie
Chapter
10

This preview shows pages 1-3. to view the full 38 pages of the document.
10. Neurophysiology 107-118 03/10/2013
- To adapt to the external enviro, we must:
Be able to perceive our environment
Plan + execute our action
- What we perceive is recreated in the cortex
If it’s not recreated, we’re not aware that it exists
Ex. Occipital cortex: where sight is recreated
Ex. Parietal cortex: GPS, position map relative to you/surroundings
oKnow where the doors are in a room even if unseen
- 2 levels of integration
1) Reflexes: mechs are simple/well-known
2) Voluntary movements: mechs are more complex/not well-known
- Organization of NS
NS CNS (brain/spinal cord) + PNS (nerves formed of axons)
oCNS = integration site
PNS somatic NS (efferent info to muscles) + autonomic NS
(efferent into to internal organs) + sensory division (sensory info to
the DNA)
Autonomic NS sympathetic/parasympathetic
- Neuron: inotropic receptor
Neuron = NS functional units
At presynaptic terminal, AP triggers Ca volt-gated channel openings
Ca enters as 2nd messenger for NT release into synaptic cleft
NT types: peptides, AAs, biogenic amines, acetylcholine
find more resources at oneclass.com
find more resources at oneclass.com

Only pages 1-3 are available for preview. Some parts have been intentionally blurred.

oCommon in CNS: glutamate (excitatory) + GABA (inhibitory)
oAch = NT neuromuscular junction
Synaptic cleft NT binds to postsynaptic ionotropic receptor or a
ligand-gated channel synaptic potential (excitatory or inhibitory)
via influx of (+)ve Na
Termination via:
oSynaptic cleft enzymes that metabolize it
oNT endocytosis by the presynaptic terminal
- NT = came from presynaptic terminal after depolarizing stimulus +
has specific postsynaptic receptors
- NTs classified according to chem structure. Categories include:
Acetylcholine
Biogenic Amines
Amino Acids
Purines
Gases/Lipids
Neuropeptides
- NT action depends on its receptor
Ex. Ach acts on nicotinic receptors to depolarize skel musc cells
(ionotropic) OR on muscarinic receptors to hyperpolarize cardiac
musc cells (metabotropic)
Ex. GABA acts on GABA-a (ionotropic) or GABA-b (metabotropic)
- Neuron: temporal and spatial summation
Graded postsynaptic potentials from successive synaptic potential
summation, which can exhibit
oTemporal summation: 1 terminal activated in rapid succession
oSpatial summation: several activated simultaneous terminals
find more resources at oneclass.com
find more resources at oneclass.com

Only pages 1-3 are available for preview. Some parts have been intentionally blurred.

EPSP: selective postsynaptic neuron to Na flow enter/depolarize
IPSP: selective to K flow leave/hyperpolarize
AP if membrane potential crosses threshold (from -70 -50 = AP)
- Neuron: circuits
NS power via cortical circuits forms by neurons
Only simple repeating principles are known
oConnections that diverge to spread signal to +neurons
oConverge to integrate signals from +neurons
oReverberate to hold info in memory
oMake parallel after-discharges to give long-lasting effects
Sensory Receptors: classification
Anatomical location of stimulus
oA) exteroceptors: body’s surface to receive enviro info
(vision/smell/taste/touch/P/vibration/temperature/pain)
oB) viseroceptors: BVs/internal organs (automatic control info)
oC) proprioceptors: muscles/articulation (body position info)
Type of Stimulus
oA) mechanoreceptors: detects mechanical stimuli
oB) thermoreceptors: thermal stimuli (temp changes the
channel’s E forms more stable conformation)
oC) photoreceptors: visual stimuli/photons
oD) chemoreceptors: molecules
oE) nociceptors: dangerous stimuli for the organism
find more resources at oneclass.com
find more resources at oneclass.com
You're Reading a Preview

Unlock to view full version