BIO 1140 Chapter Notes - Chapter 13: Repressor, Transposase, Rna Polymerase Iii
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Regulatory sequence: functions as switch, controls timing and # of gene expression. Coding sequence: determines sequence of a. a. in the proteins. Gene expression: main steps: find coding sequence to transcribe, transcription: copy sequence as mrna (single strand and able to leave nucleus, translation: ribosome reads mrna to produce protein. Prevents damage to dna when producing protein and from the protein. P(cid:396)oka(cid:396)(cid:455)otes: no (cid:374)u(cid:272)leus t(cid:396)a(cid:374)s(cid:272)(cid:396)iptio(cid:374) a(cid:374)d t(cid:396)a(cid:374)slatio(cid:374) o(cid:272)(cid:272)u(cid:396)s i(cid:374) sa(cid:373)e (cid:396)egio(cid:374). Mrna allows for simultaneous production of the same protein from a gene. Modif(cid:455) (cid:272)h(cid:396)o(cid:373)ati(cid:374) (cid:894)u(cid:374)(cid:396)avel(cid:895) to a(cid:272)(cid:272)ess ge(cid:374)e dna t(cid:396)a(cid:374)s(cid:272)(cid:396)i(cid:271)ed i(cid:374)to p(cid:396)e-mrna (cid:894)co(cid:374)tai(cid:374)s additio(cid:374)al (cid:374)u(cid:272)leotides(cid:895) p(cid:396)e-(cid:373)rna (cid:373)atu(cid:396)e i(cid:374)to (cid:373)rna leaves (cid:374)u(cid:272)leus t(cid:396)a(cid:374)slated i(cid:374)to p(cid:396)otei(cid:374)s. (cid:1007)" (cid:1009)" to (cid:271)e (cid:396)ead (cid:271)(cid:455) rna pol(cid:455)(cid:373)e(cid:396)ase ii. Non-te(cid:373)plate st(cid:396)a(cid:374)d: not used fo(cid:396) t(cid:396)a(cid:374)s(cid:272)(cid:396)iptio(cid:374). (cid:1009)" (cid:1007)". Identical to pre-mrna except pre-mrna has u and not t. Cell sig(cid:374)alli(cid:374)g a(cid:272)tivates t(cid:396)a(cid:374)s(cid:272)(cid:396)iptio(cid:374) fa(cid:272)to(cid:396) t(cid:396)igge(cid:396)s ge(cid:374)e t(cid:396)a(cid:374)s(cid:272)(cid:396)iptio(cid:374) Transcription factors: triggers transcription of certain genes to achieve specific responses.