BIO 2133 Chapter Notes - Chapter 12, 8, 2, 7: Dosage Compensation, S Phase, Dna Replication

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27 Jan 2018
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146 base pairs of dna warpped around each nucleosome; additional 40-50 base paris btwn each nuecleosome; total = When present in several levels of compaction within the chromatin fiber, dna is inaccessible to interact with other important dna-bidning proteins. Phosphorylation phosphate groups added to hydrozyl groups of aa serine and histidine, introducing ve charge on the protein. Heterochromatin euchromatin: parts of chromosome that are uncoiled; transcriptional proteins and enzymes are able to gain access to dna. Inactive lack genes or contain genes that are repressed: replicate later in the s phase of cell cycle. Position effects: position of gene or group of genes relative to all other genetic material may affect their expression; certain heterochromatic areas from one chromosome are translocated to a new site on the same or. 2 another nonhomologous chromosome, genetically active areas sometimes become genetically inert if they lie adjacent to the translocated heterochromatin. Eukaryotic genomes demonstrate complex sequence organization characterized by repetitive dna.

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