BIO 2135 Chapter Notes - Chapter DigiDiv: Thymidylate Synthase, Parabasalid, Bikont

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New classification splits kingdom into 6 supergroups. Ancestral protist = sessile cell attached to substrate, uses phagocytosis. Centrosome then organized cellular content, created an internal transport system. Microtubules grow from centrosome, push, change shape of cell a cell can now move. Molecular motors (kinesin moves away from centriole, dynein moves towards) Early form of cellular movement = no particular organization of microtubules. A daughter centriole became an organizing center, cytoplasmic flow can pull the cell across the substrate. Protoflagellum used to create water currents to get food, 9+2 organization of microtubular core with dynein arms. In unikonts, the genes for thymidylate synthetase and dihydrofolate reductase are separate. Duplication of centriole, paired flagella = bikont. Fusion of previously mentioned genes derived unikonts came first? maybe. Storage of genetic information in multiple linear strands, chromosomes fast replication. Nuclear organization chromosomes surrounded by nuclear envelope, specialized compartment, separated from cytoplasm. Endomembrane system invagination of plasma membrane.

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