HSS 3305 Chapter Notes - Chapter 12 & 14: Pulmonary Embolism, Varicose Veins, Pulmonary Alveolus

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Causes of circulatory disturbances virchow triad defines three factors leading to venous thrombosis. Intravascular thrombi: within the arteries and heart; in vascular system and in the heart. Aneurysms (outpouchings): excessive dilation of a portion of the vascular system or damage of blood vessels walls. Varicosities (tortuosity): excessive dilation or damage of blood vessels walls. Shock: low of systemic blood pressure leading to circulatory failure and collapse. Hypertension: high systemic blood pressure leading to damage to the heart and blood vessels. Small pulmonary embolism segment of lung supplied by obstructed pulmonary artery undergoes necrosis resulting in pulmonary infarct; absence of anastomosis: alveolar septa break down leading to pulmonary alveoli distended with blood. Infarction does not always follow a pulmonary embolism because anastomoses provide an alternative for blood flow: symptoms dyspnea, pleuritic chest pain (rubbing of pleural surfaces), cough, bloody sputum. Dissecting aneurysm of the aorta splitting of middle layer consisting of elastic and muscle tissues; severe chest and back pain.

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