BIOC39H3 Chapter Notes - Chapter 6-14: Adaptive Immune System, Natural Killer Cell, Innate Immune System
Document Summary
1-7 immune system cells with different functions all derive from hematopoietic stem cells. Leukocytes white blood cells (main cells of immune system: generated continually in a development process called hematopoiesis, anatomical site changes with age; Small lymphocyte production of antibodies (b cells) or cytotoxic and helper functions (t cells) Dendritic cell activation of t cells and initiation of adaptive immune response. Plasma cell fully differentiated form of b cell that secretes antibodies. Mast cell expulsion of parasites from body through release of granules containing histamine and other active agents. Natural killer cell kills cells infected with certain virus. Activation of t cells and initiation of immune response. Eosinophil killing of antibody-coated parasites through release of granule contents. Megakaryocyte platelet formation, wound repair in bone marrow. Blood cells are short-lived must be constantly renewed; cells divide to give further hematopoietic stem cells = self renewal. Daughter cells can be more mature stem cells and commit to being: 1.
