Chapter 11 Study Guide

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School
University of Toronto Scarborough
Department
Biological Sciences
Course
BIOA01H3
Professor
Mark Fitzpatrick
Semester
Winter

Description
Chapter 11 DNA and Its Role in Heredity Evidence that Gene is DNA Frederick Griffith -developed transforming principle -living S strain when injected in the mouse can result in death -living R strain is not harmful -heated (deformed) S strain is injected, mouse remains healthy -but when heated S strain is mixed with R strain and injected in the mouse, the mouse is dead -it suggests that cells in R strain are able to transform cells in S strain genetically and cause it to become active Oswald Avery -stated when DNA of molecules is destroyed, transforming principle is lost as well -added RNase, protease, and DNase separately to the titrated heated S strain and R strain mixture -the mixture where DNase is added results in R strain bacteria only, S strain is gone ->DNase destroys the DNA in S strain, preventing it from transforming to functioning cells -the mixture where RNase and protease are added result in both S and R strain -this proves DNA is the transforming substance Hershey-Chase Experiment -used
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