BIOB33H3 Chapter Notes -Melanocyte, Elastic Fiber, Keloid

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20 Sep 2013
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Stem cells in the epithelial and connective tissue. Cells of stratum basale rapidly divide and begin to migrate along edges of wound to replace missing epidermal cells. Microphages patrol the damage of the dermis. Divisions by fibroblasts and mesenchymal cells produce mobile cells that invade the deeper areas of injury. Endothelial cells of damaged blood vessels also begin to divide and capillaries follow the fibroblasts enhancing circulation. Combination of blood clot, fibroblasts and extensive capillary network = granulation tissue: dermis contains an abnormally large number of collagen fibers and relatively few blood vessels. Formation of rather inflexible, fibrous, noncellular scar tissue can be considered a practical limit of the healing process. Thick raised area of scar tissue keloid (covered by a shiny smooth epidermal surface)

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