HLTB21H3 Chapter : Smallpox (Chart-form with labels as indicated in the review)

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29 Apr 2011
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Smallpox: historical context, science contributions, impact on populations, related etiology, epidemiology, transmission, contributors of knowledge (2), vaccination-related. The disease preceded cortes" arrival in mexico (1520) Among the crew was a smallpox infected individual. Smallpox was the reason that the aztecs did not pursue the demoralized spaniards. Smallpox made pizarro"s success in south america possible. Arrived in peru by land in 1526, killing much of the inca population. Evidence found in egyptian mummies dated 1570-1080 bc. Smallpox along with malaria has contributed to the decline of the roman empire. The huns were infected in either persia or india. Small pox contributed to the settlement of north america by the french english. Has about 200 genes, 35 of which are believed to be involved in virulence. There are two pathologic varieties of the smallpox virus: 1) variola major the deadlier form, frequently killed up to 25% of its victims. 2) variola minor milder pathogen, fatality rate of ~2%

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