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Chapter 3

Chapter 3 - Neuronal Membrane at Rest

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Janelle Leboutillier

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Chapter 3The Neuronal Membrane at Rest 85108 IntroductionThe axonal membrane as properties that enable it to conduct a special type of signalthe nerve impulse or action potentialthat overcomes biological constraintsCells capable of generating and conducting action potentials which include both nerve and muscles cells are said to have excitable membraneThe action in action potential occurs at the cell membraneWhen a cell w excitable membrane is not generating impulses it is said to be at rest In the resting neuron the cytosol along the inside surface of the membrane has aelectrical charge compared to the outsideresting membrane potentialresting potentialThe action potential is simply a brief reversal of this conditionthe inside of the membrane becomesw respect to the outsideWe need to understand how neurons signal one anotherThe Cast of ChemicalsCytosol and Extracellular FluidWater is the main ingredient of the fluid inside the neurons the ICF or cytosol and the fluid that bathes the neuron the ECF Electrically charged atomsionsare dissolved in this water and are responsible for the resting and action potentialsWater The most important property of water is its uneven distribution of electrical charge covalently bonded O atom has greater affinity for electrons than H atom O atom acquires a netcharge bc of extra electrons HO is said to be a polar 2molecule held together by polar covalent bonds It makes wateran effective solvent of other charged or polar molecules other polar molecules tend to dissolve in waterIons Atoms or molecules that have a net electrical charge are ions ie Na and Cl are held by ionic bond Slat dissolves readily in water bc the charged portion of the water molecule have a stronger attraction for the ions that they have for each othery The electrical charge of an atom depends on the difference bw the number of protons and electrons y When the difference is 1 the ion is said to be monovalent when difference is 2 the ion is divalent y Ions w charge are called cations ions wcharge are called anionsThe Phospholipid MembraneSubstances that can dissolve in water are said to be waterloving hydrophilic
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