Textbook Notes (368,164)
Canada (161,688)
Neuroscience (289)
NROC61H3 (42)
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Department
Neuroscience
Course
NROC61H3
Professor
Le Boutillier
Semester
Fall

Description
Sharif AlkatibEskandari NeuralImmune Interactions in Health and DiseaseCytokines produce signals read by the brain to indicate a site of inflammation leading to a fever and sicknessbehaviorsCNSGlucorticoidsCRHParaventricular nucleushypophyseal portal blood supplyArgine vasopressinStimulate the release of adrenocorticotropin ACTH from APCauses adrenal glands to release glucorticoidsModulated by serotonergic cholinergic and catecholaminergic systemsNegative feedback HPA axisGABABZDInhibit serotonininduced CRH secretionInflammatory response cytokine expression IC trafficking immune cell maturation and differentiation Low levelsShift from proinflammatory increased interleukins and tumor necrosis factor alpha to anti
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