Chapter 16.docx

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Department
Neuroscience
Course
NROC61H3
Professor
Janelle Leboutillier
Semester
Winter

Description
Chapter 16The HT homeostasis and motivated behaviorThe Ht plays important roles in body temp fluid balance and energy balanceA response occurs when there is an imbalance in homeostasis 1 Humoral response appropriate pituitary hormones released into blood 2 Visceromotor ANS outputs adjusted accordingly 3 Somatic motor somatic motor behavioral responseThe long term regulation of feeding behaviorWe eat to maintain energy at a certain level below which cell death and organism death will occur Energy balancePrandial state After we eat we are in a prandial state blood is filled w nutrients There are two types of energy storage macromolecules assembled by anabolic metabolism glycogen finite reserves in liver and skeletal muscle and triglycerides stored by adipose tissue Postabsorptive state Catabolism breaks down the complex macromolecules into simpler nutrients for cellular respiration Glucose is used by all cells and fatty acids and ketones are needed for non neuronsWe must have a balance between catabolism and anabolism Too much intake adiposity increases obesity Catabolismanabolismadiposity decreasesstarvation Hormonal and ht regulation of body fat and feedingNeurons in periventricular zone detect decrease in release of fat cell protein and neurons in lateral hypothalamus will induce feeding behaviorBody fat and food consumption o Lipostatic hypothesis the brain has a set point for adiposity that will incite defensive behavior if there are alterations too much eating reduce adiposity and vice versa o Coleman found that obese mice lacked ob ob gene in their DNA When parabiosed fused with normal mice their adiposity decreased o Friedman found leptin to the protein that is released by adipose tissue that acts directly on ht neurons that decrease appetite and increase energy expenditureHypothalamus and feeding o Hetherington and Ranson found that lesions in hypothalamus cause obesity starvationLateral hypothalamus lateral hypothalamic syndrome caused by damage to LHT causes loss in appetite anorexiaVentromedial hypothalamus ventromedial hypothalamic syndrome caused by damage to VHT causes obesityEffects of elevated leptin on HT
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