NROB60H3 Chapter Notes - Chapter 6: Axon Terminal, Choline, Cytosol
9 Dec 2020
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Criteria for neurotransmitter, the molecule must: synthesized and stored in the presynaptic neuron. released by the presynaptic axon terminal upon stimulation. 1: produce a response in the postsynaptic cell that mimics the response produced by the release of neurotransmitter from the presynaptic neuron. It can be called immunohistochemistry when applied to a thin section of tissue (including the brain). Injected in the bloodstream of an animal to enhance the immune response. Antibodies have created that bind to an antigen (transmitter chosen) Antibodies are taken out and marked to be inserted again after. We can cut through the brain and observed the antibodies present thanks to their marker. It used to demonstrate that the transmitter and its synthesizing enzyme are contained in the same neuron or better yet, in the same axon terminal. = to confirm if a cell synthesize a particular protein or peptide. A complementary strand is constructed in the lab that will bind tightly (=probe)
