PSYB32H3 Chapter Notes - Chapter 12: Nicotinic Acetylcholine Receptor, Substance Intoxication, Coronary Artery Disease

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Substance dependence is diagnosed with physiological dependence if tolerance or withdrawal is present more severe. The less severe substance abuse the person must experience one of the following: failure to fulfil obligations, exposure to physical dangers, legal problems, social or interpersonal problems. Substance intoxication is when a substance effects the cns and creates maladaptive behavioural or cognitive effects. The term abuse refers to excessive and harmful aspects of alcohol. A person with alcohol dependence may experience tolerance or withdrawal. The person become anxious, restless, and tremors of muscles with higher blood pressure. In rare cases a person may experience delirium tremens person has hallucinations that are primarily visual. Alcohol in the blood of people who have built a tolerance is very low because the body adapts the drug and processes it better. Tolerance may be due to the number or sensitivity changes of gaba or glutamate receptors.

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